Mounjaro is a prescription medication developed by Eli Lilly, containing the active ingredient tirzepatide.It is a once-weekly injectable drug approved for the treatment of type 2 diabetes and, more recently, for chronic weight management.Mounjaro works by mimicking two hormonesβglucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP)βto regulate blood sugar levels and suppress appetite .
Mounjaro is approved for adults with type 2 diabetes to improve glycemic control.Clinical trials have demonstrated that it can lower HbA1c levels by up to 2.4% over 40 weeks .
In addition to diabetes management, Mounjaro has been approved for chronic weight management in adults with obesity (BMI β₯30) or overweight (BMI β₯27) with at least one weight-related comorbidity.Clinical studies have shown that patients can lose up to 21.8 kg over 72 weeks when combined with diet and exercise .
Tirzepatide is a dual GIP and GLP-1 receptor agonist.By activating both receptors, it enhances insulin secretion, suppresses glucagon release, and slows gastric emptying, leading to improved blood sugar control and reduced appetite .
Nausea
Diarrhea
Decreased appetite
Vomiting
Constipation
Indigestion
Stomach pain
Risk of thyroid C-cell tumors (based on animal studies)
Pancreatitis
Hypoglycemia (especially when used with insulin or sulfonylureas)
Acute kidney injury
Severe gastrointestinal issues
Gallbladder disease
Due to the potential risk of thyroid cancer, Mounjaro is contraindicated in individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 .
The SURPASS clinical trial program evaluated the efficacy of tirzepatide in type 2 diabetes management.Results indicated significant reductions in HbA1c levels and body weight compared to placebo and other diabetes medications .
The SURMOUNT trials assessed the impact of tirzepatide on weight loss.Participants experienced substantial weight reductions, with some losing over 20 kg over 72 weeks, highlighting its potential as an effective weight management therapy .
Adults with type 2 diabetes seeking better blood sugar control
Adults with obesity (BMI β₯30) or overweight (BMI β₯27) with weight-related health conditions.
History of pancreatitis
Personal or family history of medullary thyroid carcinoma
Multiple endocrine neoplasia syndrome type 2
Pregnancy or breastfeeding
One of the primary concerns for patients interested in using Mounjaro for weight loss is its cost. As mentioned, Mounjaro Australia cost can be a significant factor in deciding whether to begin treatment.
On average, the cost of Mounjaro in Australia starts at AUD 395 per month. This price covers the first dose and subsequent doses, but the total cost can increase based on the frequency of use and the required dosage.
Given that Mounjaro Australia prescription is only available privately, patients will need to factor in the cost of consultations with a healthcare provider who can prescribe the medication. The overall monthly expense may therefore reach beyond just the price of the medication itself.
For comparison, other weight loss treatments, such as Ozempic and Wegovy, are similarly priced but offer different mechanisms of action. Both are also GLP-1 agonists, yet Mounjaro stands out due to its dual-receptor approach, which may offer more significant results for certain patients.
However, Mounjaroβs cost can be a barrier for long-term use, particularly for those without the means to cover the ongoing expense. As a result, individuals are encouraged to speak with their healthcare provider about other potential treatments, including lifestyle interventions or surgical options, depending on the severity of their weight condition.
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While Mounjaro has shown efficacy in weight loss and diabetes management, some users have reported psychological side effects, including anxiety and depression.It's essential for healthcare providers to monitor patients for any mood changes and provide appropriate support .
Dolores Catania's Experience: The reality TV star shared that she gained 20 pounds after Mounjaro's effectiveness diminished, highlighting the importance of individualized treatment plans .
Katie Price's Advocacy: Katie Price has been using Mounjaro to manage her son Harvey's obesity, emphasizing the drug's potential benefits when used under medical supervision .
Mounjaro represents a significant advancement in the treatment of type 2 diabetes and obesity.Its dual-action mechanism offers enhanced efficacy in managing blood sugar levels and promoting weight loss.However, potential side effects and contraindications necessitate careful consideration and consultation with a healthcare provider before initiating treatmen